• Youfu Ke, Jinbao Pu, and Junxian Zheng.
• The University of Hong Kong, School of Chinese Medicine, 999077, Hong Kong, China. Electronic address: keyoufu@gmail.com.
• Complement Ther Med. 2013 Dec 1; 21 (6): 609-12.

ObjectiveTo evaluate the efficacy and safety of wuling powder and modified tianma gouteng decoction as an open add-on therapy for treating essential hypertension (EH).Methods72 cases of EH patients took wuling powder and modified tianma gouteng decoction for 2 weeks to treat EH without changing their former medication. New York Heart Association (NYHA) heart function classification, heart rate, blood pressure and 6-min walking test were evaluated before and after treatment.ResultsWuling powder and modified tianma gouteng decoction decreased the EH patients' heart rate, systolic pressure, diastolic pressure and increased the 6-min walking distance very significantly (P<0.01). The total effective rate on blood pressure was 91.7%, and the total effective rate on NYHA heart function improvement was 95.1%. No serious side effect appeared.ConclusionFrom this study, treating EH with wuling powder and modified tianma gouteng decoction as an open add-on therapy seems to be effective and safe. Further randomized trials are needed to test the positive findings.Copyright © 2013 Elsevier Ltd. All rights reserved.

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