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J. Neurosci. Methods · Aug 2010
A surgical technique of spinal cord cell transplantation in amyotrophic lateral sclerosis.
- Miguel Blanquer, Miguel Angel Pérez-Espejo, Juan F Martínez-Lage, Francisca Iniesta, Salvador Martinez, and Jose M Moraleda.
- Transplant and Cell Therapy Unit, "Virgen de la Arrixaca" University Hospital (University of Murcia), Faculty of Medicine, Ctra. de Cartagena, km 7, E-30120 El Palmar, Murcia, Spain. miguelblanquer@gmail.com
- J. Neurosci. Methods. 2010 Aug 30; 191 (2): 255-7.
AbstractWe report an original method for implanting bone marrow stem cells within the spinal cord parenchyma. This method was used for the experimental treatment of patients diagnosed with amyotrophic lateral sclerosis. The methodology is reproducible and devoid of major complications even in patients showing significant spinal atrophy. Therefore, this report describes a surgical procedure that could be used in other experimental treatments involving the intraspinal delivery of stem cells.Copyright (c) 2010 Elsevier B.V. All rights reserved.
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