• Li-jun Liu, Zhan-cang Xue, Guo-qing Yang, and Xiu-ming Zhang.
• The First Municipal Hospital, Shijiazhuang 050011, Hebei, China.
• Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2004 Sep 1; 16 (9): 544-6.

ObjectiveTo seek the optimal time window for minimally invasive aspiration and drainage of the hematoma in patients with intracerebral hemorrhage.MethodsOne hundred and twenty-six patients with intracerebral hemorrhage were divided into two groups in terms of the operation time window: ultra-early stage group (within 6 hours) and early stage group (6-24 hours). European stroke scale (ESS) score and Bartherl index (BI) were used to evaluate the improvement of neurological function.ResultsThere were no significant differences between the two groups in ESS score, complications, and past medical history on hospital admission. Also no difference existed in the volume of hematoma in different regions of the brain between the two groups, including putamen thalamus and brain lobes. However, one month after the onset, mean ESS score was 64.76+/-7.12 and the mean BI was 66.39+/-7.23 in the ultra-early stage group (non-survivors were excluded), whereas in the early stage group, they were 59.21+/-8.63 and 61.91+/-8.31 (non-survivors were excluded too), respectively (both P<0.01). Three months after the mean BI was 79.46+/-13.29 in the ultra-super early stage group and 72.32+/-11.86 in the early stage group, and the difference in the two groups was significant (P<0.01). Though surgery in the ultra-early stage gave better results than that in early stage, no marked difference in mortality was found between the two groups (P>0.05).ConclusionThe aspiration and drainage of the hematoma should be done as early as possible (within 6 hours of the onset) provided that the patients are fit to undergo the surgery.

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