• Ugeskrift for laeger · Sep 2005

    Case Reports

    [Imiquimod treatment of lentigo maligna to dermoscopic and histologic clearance].

    • Henrik F Lorentzen and Kaare Weismann.
    • Odense Universitetshospital, Naevusklinikken, Dermatologisk Afdeling, og Hørsholm Sygehus, Dermatologisk Klinik. lorentzen@dadlnet.dk
    • Ugeskr. Laeg. 2005 Sep 26; 167 (39): 3696-7.

    AbstractImiquimod is an immune system-modifying drug that switches the immune system to a Th1 response, enabling it to defeat virus-infected and neoplastic cells. We report on a 94-year-old woman with a large lentigo maligna (LM) on her cheek whom we treated with imiquimod 5% cream. Dermoscopy was used to identify the most suspect areas of the lesion for biopsy and in follow-up. By week 19 the lesion was cleared, and no remnants of the lesion were seen by dermoscopy or histology. Published LM cases treated with imiquimod are reviewed.

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