• J Appl Lab Med · Apr 2021

    How SARS-CoV-2 Transformed the Clinical Laboratory: Challenges and Lessons Learned.

    • Jonathan M Tsai, Nicole V Tolan, Athena K Petrides, Sanjat Kanjilal, Manfred Brigl, Neal I Lindeman, Yen-Der Li, Milenko J Tanasijevic, Sankha S Basu, and MelansonStacy E FSEFDepartment of Pathology, Brigham and Women's Hospital, Boston, MA.Harvard Medical School, Boston, MA..
    • Department of Pathology, Brigham and Women's Hospital, Boston, MA.
    • J Appl Lab Med. 2021 Apr 6.

    AbstractThe COVID-19 pandemic has made a devastating impact on global health and continues to challenge healthcare infrastructure and delivery. The clinical laboratories were no exception as they are responsible for diagnostic testing that dictates many clinical, infection control and public health decisions. Information technology and laboratory management tools are critical assets for maintaining and adapting operations in response to crises and when utilized effectively, promote the integration between the clinical laboratory specialties (e.g., chemistry, hematology, microbiology, and molecular pathology). During the COVID-19 pandemic, our systems and processes were strained due to high testing volumes, demand for rapid turnaround times, supply chain constraints, and constantly evolving testing algorithms and result interpretations as our knowledge of the virus and of diagnostics increased over time. In this report, we describe those challenges and subsequent adaptations made by each clinical laboratory section. We hope these details help provide potential solutions and approaches for other hospitals facing COVID-19 surges or other future pandemics.© 2021 American Association for Clinical Chemistry.

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