• Niger Postgrad Med J · Oct 2020

    Clinical characteristics, predictors of symptomatic coronavirus disease 2019 and duration of hospitalisation in a cohort of 632 Patients in Lagos State, Nigeria.

    • Olufemi A Erinoso, Kikelomo Ololade Wright, Samuel Anya, Abimbola Bowale, Olusola Adejumo, Sunday Adesola, Bodunrin Osikomaiya, Bamidele Mutiu, Babatunde Saka, Ayodeji Falana, Disu Ola-Ayinde, Ephraim I Akase, Henry Owuna, Hussein Abdur-Razzaq, Dayo Lajide, Oliver Ezechi, Olusegun Ogboye, Akin Osibogun, and Akin Abayomi.
    • Department of Oral and Maxillofacial Surgery, Lagos State University Teaching Hospital, Lagos State, Lagos, Nigeria.
    • Niger Postgrad Med J. 2020 Oct 1; 27 (4): 285-292.

    ObjectiveThe clinical spectrum of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is still evolving. This study describes the clinical characteristics and investigates factors that predict symptomatic presentation and duration of hospitalisation in a cohort of coronavirus disease 2019 (COVID-19) patients managed in Lagos, Nigeria.MethodologyThis was a retrospective assessment of patients hospitalised with COVID-19 disease in six dedicated facilities in Lagos, Nigeria, between April 1st and May 31st 2020. Participants were individuals with laboratory-confirmed SARS-CoV-2 infection. The outcome measures were presence of symptoms and duration of hospitalisation. Demographic and comorbidity data were also obtained. Statistical analysis was done using STATA 15.0 software, with P < 0.05 being considered statistically significant.ResultsA total of 632 cases were analysed. The median age was 40 years (IQR: 30.5-49); male patients accounted for 60.1%. About 63% of patients were asymptomatic at presentation. Among the symptomatic, the most common symptoms were cough (47.4%) and fever (39.7%). The most common comorbidities were hypertension (16.8%) and diabetes (5.2%). The median duration of hospitalisation was 10 days (IQR: 8-14). Comorbidities increased the odds of presenting with symptoms 1.6-fold (P = 0.025) for one comorbidity and 3.2-fold (P = 0.005) for ≥2 comorbidities. Individuals aged ≥50 years were twice as likely to be hospitalised for more than 14 days compared to individuals aged <50 years (P = 0.016).ConclusionMost individuals had no symptoms with comorbidities increasing the likelihood of symptoms. Older age was associated with longer duration of hospitalisation. Age and comorbidities should be used for COVID-19 triaging for efficient resource allocation.

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