• Magn Reson Med · Feb 2016

    Modified wideband three-dimensional late gadolinium enhancement MRI for patients with implantable cardiac devices.

    • Shams Rashid, Stanislas Rapacchi, Kalyanam Shivkumar, Adam Plotnik, J Paul Finn, and Peng Hu.
    • Department of Radiological Sciences, David Geffen School of Medicine, University of California, Los Angeles, California, USA.
    • Magn Reson Med. 2016 Feb 1; 75 (2): 572-84.

    PurposeTo study the effects of cardiac devices on three-dimensional (3D) late gadolinium enhancement (LGE) MRI and to develop a 3D LGE protocol for implantable cardioverter defibrillator (ICD) patients with reduced image artifacts.Theory And MethodsThe 3D LGE sequence was modified by implementing a wideband inversion pulse, which reduces hyperintensity artifacts, and by increasing bandwidth of the excitation pulse. The modified wideband 3D LGE sequence was tested in phantoms and evaluated in six volunteers and five patients with ICDs.ResultsPhantom and in vivo studies results demonstrated extended signal void and ripple artifacts in 3D LGE that were associated with ICDs. The reason for these artifacts was slab profile distortion and the subsequent aliasing in the slice-encoding direction. The modified wideband 3D LGE provided significantly reduced ripple artifacts than 3D LGE with wideband inversion only. Comparison of 3D and 2D LGE images demonstrated improved spatial resolution of the heart using 3D LGE.ConclusionIncreased bandwidth of the inversion and excitation pulses can significantly reduce image artifacts associated with ICDs. Our modified wideband 3D LGE protocol can be readily used for imaging patients with ICDs given appropriate safety guidelines are followed.© 2015 Wiley Periodicals, Inc.

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