• Song Sun, Liang Han, Yufeng Li, Xudong Yu, Binghao Bao, Hong Zhou, and Ziqi Gong.
• Department of Surgery, Beijing Changping Hospital of Traditional Chinese Medicine.
• Medicine (Baltimore). 2019 Jul 1; 98 (30): e16479e16479.

BackgroundPremature ejaculation is a common sexual dysfunction disease in adult males. There are many clinical trials shown that dorsal penile nerve block can prolong the ejaculation latency to a certain extent in the vagina. In this study, we aim to use a meta-analysis to evaluate the efficacy and safety of dorsal penile nerve block for premature ejaculation.Methods And AnalysisWe will search for PubMed, Cochrane Library, AMED, EMbase, WorldSciNet, Nature, Science online and China Journal Full-text Database (CNKI), China Biomedical Literature CD-ROM Database (CBM), and related randomized controlled trials included in the China Resources Database. The time is limited from the construction of the library to February 2019. The quality of the included RCTs will be evaluated with the risk of bias (ROB) tool and evidence will be evaluated by GRADE. Data analysis will be used the special software like RevMan (version 5.3) and EndNote X7.ResultsThe results of this meta-analysis will be submitted to a peer-reviewed journal for publication.Ethics And DisseminationThis systematic review will evaluate the efficacy and safety of dorsal penile nerve block for premature ejaculation. Because all of the data used in this systematic review and meta-analysis has been published, this review does not require ethical approval. Furthermore, all data will be analyzed anonymously during the review process Trial.Trial Registration NumberPROSPERO CRD42019119691.

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