• Southern medical journal · May 1976

    Clinical significance of the biotransformation of inhalation anesthetics.

    • B R Brown.
    • South. Med. J. 1976 May 1; 69 (5): 554-6.

    AbstractInhalation anesthetics, a class of drugs formerly believed to be biologically inert, are now recognized to undergo considerable biotransformation. The viscerotoxicity of certain anesthetics on kidney and liver can be explained in terms of metabolism. The entity of "halothane hepatitis" remains mechanistically and diagnostically a mystery, but if it exists, it could be due to abnormalities of biotransformation.

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