• Clinics in perinatology · Dec 2015

    Review

    Mechanical Ventilation and Bronchopulmonary Dysplasia.

    • Martin Keszler and Guilherme Sant'Anna.
    • Department of Pediatrics, Women and Infants Hospital of Rhode Island, Alpert Medical School of Brown University, 101 Dudley Street, Providence, RI 02905, USA. Electronic address: mkeszler@wihri.org.
    • Clin Perinatol. 2015 Dec 1; 42 (4): 781-96.

    AbstractMechanical ventilation is an important potentially modifiable risk factor for the development of bronchopulmonary dysplasia. Effective use of noninvasive respiratory support reduces the risk of lung injury. Lung volume recruitment and avoidance of excessive tidal volume are key elements of lung-protective ventilation strategies. Avoidance of oxidative stress, less invasive methods of surfactant administration, and high-frequency ventilation are also important factors in lung injury prevention. Copyright © 2015 Elsevier Inc. All rights reserved.

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