• Shigeki Arizono, Hiroyoshi Isoda, Yoji S Maetani, Yuusuke Hirokawa, Kotaro Shimada, Yuji Nakamoto, and Kaori Togashi.
• Department of Diagnostic Imaging and Nuclear Medicine, Graduate School of Medicine, Kyoto University Kyoto, Japan. arizono@kuhp.kyoto-u.ac.jp
• J Magn Reson Imaging. 2008 Sep 1; 28 (3): 685-90.

PurposeTo evaluate the image quality of high-spatial-resolution three-dimensional magnetic resonance cholangiography (MRC) with a high-sampling-efficiency technique (sampling perfection with application optimized contrasts using different flip angle evolutions [SPACE]) in comparison with a conventional constant flip angle (FA) sequence at 3T.Materials And MethodsEighteen volunteers were examined on a 3T MR unit using MRC imaging performed with three different free-breathing three-dimensional T2-weighted turbo spin-echo (TSE) sequences: 1) SPACE (spatial resolution, 1.1x1.0x0.84 mm), 2) constant FA (1.1x1.0x0.84 mm), and 3) SPACE at a higher resolution (SPACE HR; 1.0x0.9x0.644 mm). A five-point scale was used to compare overall image quality and visualization of the third branches of the bile duct (B2, B6, and B8). Depictions of cystic duct insertion and the highest order of bile duct visible were also compared.ResultsMRC with SPACE and SPACE HR sequences produced significantly better overall image quality than the constant FA sequence. In all analyses of duct visibility, SPACE and SPACE HR sequences showed higher scores than the constant FA sequence.ConclusionHigh-resolution three-dimensional MRC with SPACE at 3T allows high-quality imaging of the biliary tract, and has the ability to depict nondilated intrahepatic bile ducts (IHBD) in healthy volunteers.Copyright (c) 2008 Wiley-Liss, Inc.

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