• Singap Med J · Dec 2014

    Review

    Current status of endotherapy for chronic pancreatitis.

    • KwekAndrew Boon EuABDepartment of Gastroenterology and Hepatology, Changi General Hospital, 2 Simei Street 3, Singapore 529889. andrew_kwek@cgh.com.sg., Tiing Leong Ang, and Amit Maydeo.
    • Department of Gastroenterology and Hepatology, Changi General Hospital, 2 Simei Street 3, Singapore 529889. andrew_kwek@cgh.com.sg.
    • Singap Med J. 2014 Dec 1; 55 (12): 613-20.

    AbstractChronic pancreatitis is associated with varied morphological complications, including intraductal stones, main pancreatic ductal strictures, distal biliary strictures and pseudocysts. Endoscopic therapy provides a less invasive alternative to surgery. In addition, extracorporeal shockwave lithotripsy improves the success rate of endoscopic clearance of intraductal stones. However, recent data from randomised trials have shown better long-term outcomes with surgical drainage for obstructive pancreatic ductal disease. In patients with distal biliary strictures, stent insertion leads to good immediate drainage, but after stent removal, recurrent narrowing is common. Endoscopic drainage of pancreatic pseudocysts has excellent outcome and should be accompanied by pancreatic ductal stenting when a ductal communication is evident. In those who remain symptomatic, endoscopic ultrasonography-guided coeliac plexus block may provide effective but short-term pain relief. In this review, we present the current evidence for the role of endotherapy in the management of patients with chronic pancreatitis.

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