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Case Reports
[Livedo-like dermatitis (Nicolau's syndrome) after injection of Copolymer-1 (Glatiramer acetate)].
- C Gaudez, S Regnier, S Aractingi, and O Heinzlef.
- Service de Dermatologie, Hôpital Tenon, Paris. francois.caroline.gaudez@wanadoo.fr
- Rev Neurol France. 2003 May 1; 159 (5 Pt 1): 571-3.
AbstractWe report the first case of a 33-year-old woman with multiple sclerosis, who developed a livedo-like dermatitis after injection of Copolymere-1. This disease is characterized by the development of acute violent pain during or immediately after injection, and a livedo-like plaque followed by necrosis corresponding to an arterial ischemia by vasospasm or thrombosis. Early treatment with vasoactive and anticoagulation agents is required. Surgery may be necessary.
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