• Nijmeh Al-Atiyyat and Abdullah Obaid.
• Hashemite University, Faculty of Nursing.
• Int J Palliat Nurs. 2017 Jan 2; 23 (1): 13-17.

AimTo identify which of the examined agents or modalities were effective in the management of chemotherapy-induced peripheral neuropathy (CIPN).MethodsPubMed, CINAHL, Medline, Science Direct and Ovid databases were used to search keywords. The literature search identified 59 potentially relevant studies; after removing duplicates and reviewing titles a total of 26 articles were examined. In the end, a total of 18 studies met the inclusion criteria.FindingsThe preliminary data for using lafutidine, acupuncture and sweet bee venom pharmacopuncture indicate that they may be useful in CIPN management. The use of duloxetine was effective and supported as a management of CIPN; likewise the use of scrambler therapy significantly decreased CIPN pain. However, the use of electroacupuncture and topical amitriptyline and ketamine was not supported.ConclusionThe use of duloxetine was effective in CIPN management. Further studies with larger sample size are needed.

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