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- H Gil, S Perrin, J-L Dupond, N Meaux-Ruault, C Hafsaoui, S Limat, and N Magy-Bertrand.
- Service de médecine interne, CHU Jean-Minjoz, 1, boulevard Fleming, 25000 Besançon, France. hgil@chu-besancon.fr
- Rev Med Interne. 2010 Jun 1; 31 (6): 403-5.
PurposeThalidomide is an effective treatment for recurrent aphthosis but its effectiveness at low dose has been rarely assessed.MethodsSingle-centre non-randomized retrospective open study.ResultsForty-seven patients were treated with thalidomide for recurrent aphthosis (41 patients) or Behçet disease (six patients). Remission was obtained with a dose of 25 mg daily. Discontinuation of treatment for side effects was not observed in this case series.ConclusionLow dose thalidomide below 50 mg daily is an effective and well tolerated treatment of aphthosis.Copyright 2010 Société nationale française de médecine interne (SNFMI). Published by Elsevier SAS. All rights reserved.
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