• Med Klin Intensivmed Notfmed · Mar 2017

    Case Reports

    [Acidosis without marked hyperglycemia : Euglycemic diabetic ketoacidosis associated with SGLT2-Inhibitors].

    • R Valek and J Von der Mark.
    • Anästhesie und Intensivmedizin, Stadtspital Triemli, Birmensdorferstraße 497, 8063, Zürich, Schweiz. ruth.valek@triemli.zuerich.ch.
    • Med Klin Intensivmed Notfmed. 2017 Mar 1; 112 (2): 145-148.

    AbstractSodium-glucose cotransporter 2 (SGLT2) inhibitors are new antidiabetic drugs that regulate blood glucose levels by increasing urinary glucose excretion. In May 2015, the U.S. Food and Drug Administration (FDA) issued a warning that SGLT2 inhibitors may lead to ketoacidosis. In this report, we describe a case of life-threatening euglycemic ketoacidosis associated with SGLT2 inhibition and evaluate possible mechanisms and triggers.

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