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Journal of anesthesia · Aug 2013
Case ReportsIntraoperative hypernatremia and polyuric syndrome induced by dexmedetomidine.
- Fuhai Ji and Hong Liu.
- Department of Anesthesiology and Pain Medicine, University of California Davis Health System, Sacramento, CA 95817, USA.
- J Anesth. 2013 Aug 1;27(4):599-603.
AbstractHypernatremia and polyuria are the main symptoms of diabetes insipidus. Polyuria is characterized by a 24-h urine volume in excess of 40-50 ml/kg in adults. Dexmedetomidine, a highly selective, short-acting intravenous alpha-2 agonist, is used as a component of anesthesia, and has been suspected to induce polyuric syndrome. We report a patient who presented with severe hypernatremia and polyuria after intravenous infusion of dexmedetomidine.
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