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Clinical rheumatology · Sep 2009
Case ReportsStiff skin syndrome versus scleroderma: a report of two cases.
- V F Azevedo, S Z Serafini, B Werner, C S Müller, C F M Franchini, and R L S L Morais.
- Spondylarthropathies Clinic, Hospital de Clínicas, Federal University of Paraná, Rebouças, Curitiba, PR CEP 80250-020, Brasil. valderilio@hotmail.com
- Clin. Rheumatol. 2009 Sep 1; 28 (9): 1107-11.
AbstractStiff skin syndrome is a rare cutaneous disease, scleroderma-like disorder that presents in infancy or early childhood with rock-hard skin, limited joint mobility, and mild hypertrichosis. Normally, it occurs in the absence of visceral or muscle involvement. Patients do not present immunologic abnormalities or vascular hyperactivity. We describe two adults who initially were diagnosed suffering from scleroderma but fit criteria for stiff skin syndrome. A review of the clinical range of this disorder and discussion of the differential diagnosis with scleroderma is presented.
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