• Leukemia research · Mar 2010

    The suggestion of a risk stratification system for febrile neutropenia in patients with hematologic disease.

    • Yong Park, Dae Sik Kim, Seh Jong Park, Hee Yun Seo, Se Ryeon Lee, Hwa Jung Sung, Kyong Hwa Park, In Keun Choi, Seok Jin Kim, Sang Cheul Oh, Jae Hong Seo, Chul Won Choi, Byung Soo Kim, Sang Won Shin, Yeul Hong Kim, and Jun Suk Kim.
    • Division of Hematology and Oncology, Department of Internal Medicine, College of Medicine, Korea University, Seoul, Republic of Korea.
    • Leuk. Res. 2010 Mar 1; 34 (3): 294-300.

    AbstractWe analyzed the prognostic factors from 259 cases of febrile neutropenia occurring in 137 patients with hematologic disease. Based on multivariate analysis, significant prognostic factors are recovery of neutropenia, respiratory infection, baseline serum albumin, baseline bicarbonate, baseline CRP, and CRP on the fifth day after antibiotic treatment. From these variables, we derived a predictive model for the prognosis of febrile neutropenia using baseline serum albumin, bicarbonate, and CRP, which could be easily checked before chemotherapy. Further studies in prospective setting are needed for the validation of this model.Copyright (c) 2009. Published by Elsevier Ltd.

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