• J. Hosp. Infect. · Mar 1985

    Randomized Controlled Trial Comparative Study Clinical Trial

    Antiseptic vs. saline lavage in purulent and faecal peritonitis.

    • S Vallance and R Waldron.
    • J. Hosp. Infect. 1985 Mar 1; 6 Suppl A: 87-91.

    AbstractA prospective randomized trial compared antiseptic solutions and normal saline as a means of preventing morbidity and mortality from residual sepsis in patients with generalized peritonitis. Fifty-three patients, all given broad-spectrum antibiotics, were entered into the study. Twenty patients received a saline lavage, 19 lavage with chlorhexidine-gluconate and 14 a saline lavage with instillation of povidone-iodine. All deaths were due either to the severity of the presenting disease or co-existing complicating conditions. The incidence of postoperative pyrexia, wound infection and duration of hospital stay of the surviving patients were unaffected by lavage grouping.

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