• British journal of cancer · Aug 2018

    Comparative Study

    Treatment and survival of rectal cancer patients over the age of 80 years: a EURECCA international comparison.

    • Yvette H M Claassen, Nina C A Vermeer, Lene H Iversen, Elizabeth van Eycken, Marianne G Guren, Pawel Mroczkowski, Anna Martling, Antonio Codina Cazador, Robert Johansson, Tamara Vandendael, Arne Wibe, Bjorn Moller, Hans Lippert, RuttenHarm J THJTDepartment of Surgery, Catharina Hospital, Eindhoven, The Netherlands.GROW: School of Oncology and Developmental Biology, University of Maastricht, Maastricht, The Netherlands., PortieljeJohanneke E AJEADepartment of Gerontology & Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Gerrit J Liefers, Fabian A Holman, van de VeldeCornelis J HCJHDepartment of Surgery, Leiden University Medical Center, Leiden, The Netherlands., and Esther Bastiaannet.
    • Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
    • Br. J. Cancer. 2018 Aug 1; 119 (4): 517-522.

    BackgroundThe optimal treatment strategy for older rectal cancer patients remains unclear. The current study aimed to compare treatment and survival of rectal cancer patients aged 80+.MethodsPatients of ≥80 years diagnosed with rectal cancer between 2001 and 2010 were included. Population-based cohorts from Belgium (BE), Denmark (DK), the Netherlands (NL), Norway (NO) and Sweden (SE) were compared side by side for neighbouring countries on treatment strategy and 5-year relative survival (RS), adjusted for sex and age. Analyses were performed separately for stage I-III patients and stage IV patients.ResultsOverall, 19 634 rectal cancer patients were included. For stage I-III patients, 5-year RS varied from 61.7% in BE to 72.3% in SE. Proportion of preoperative radiotherapy ranged between 7.9% in NO and 28.9% in SE. For stage IV patients, 5-year RS differed from 2.8% in NL to 5.6% in BE. Rate of patients undergoing surgery varied from 22.2% in DK to 40.8% in NO.ConclusionsSubstantial variation was observed in the 5-year relative survival between European countries for rectal cancer patients aged 80+, next to a wide variation in treatment, especially in the use of preoperative radiotherapy in stage I-III patients and in the rate of patients undergoing surgery in stage IV patients.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…