• Frédéric Pamoukdjian, Evelyne Liuu, Philippe Caillet, Mathilde Gisselbrecht, Stéphane Herbaud, Pascaline Boudou-Rouquette, Laurent Zelek, and Elena Paillaud.
• AP-HP, hôpital Avicenne, service de médecine gériatrique, unité de coordination en onco-gériatrie, 125, rue de Stalingrad, 93000 Bobigny, France; Université Paris 13, Sorbonne Paris Cité, laboratoire éducations et pratiques de santé (LEPS), EA3412, 93017 Bobigny, France. Electronic address: frederic.pamoukdjian@aphp.fr.
• Bull Cancer. 2017 Nov 1; 104 (11): 946-955.

AbstractCancer is a disease of the elderly as demonstrated by the epidemiological evolution of Western countries. Indeed, two third of cancers newly diagnosed occur over 65 years. However, older cancer patients have been often excluded from clinical trials in oncology and the extrapolation of cancer treatments in this population remains difficult in practice. Scientific societies recommend that a comprehensive geriatric assessment (CGA) be performed in patients aged 70 and over and selected using screening tools for frailty such as the G8 index. The CGA allows to detect aging-related vulnerabilities in various domains (comorbidities, polypharmacy, autonomy, nutrition, mobility, cognition, mood, social) and associated with adverse outcomes during cancer treatment (reduced overall survival, perioperative complications, toxicity-related chemotherapy). The CGA is allow to elaborate a personalized treatment plan in geriatric oncology. However, to date, no algorithms based on CGA is validated to guide therapeutic decision in geriatric oncology. The collaboration between geriatrician and oncologist remains essential to elaborate an appropriate therapeutic strategy and limit the situations of over- and under-treatment. This article presents the set of tools and scores used in geriatric oncology to guide the therapeutic decision.Copyright © 2017 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.

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