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Anasthesiol Intensivmed Notfallmed Schmerzther · Mar 2013
Review[Acute kidney injury--prevention, risk stratification and biomarkers].
- Daniel Bläser.
- Klinik für Anästhesiologie und Operative Intensiv medizin, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Germany. daniel.blaeser@uksh.de
- Anasthesiol Intensivmed Notfallmed Schmerzther. 2013 Mar 1;48(2):122-7; quiz 128.
AbstractAcute kidney injury influences negatively morbidity and mortality of the critically ill patient and causes increased costs by prolonged length of stay in the intensive care unit. At present the diagnosis and classification of acute kidney injury is derived from the RIFLE and AKIN criteria based on serum creatinine and urine output. The possible pre-, intra- and postrenal causes of acute kidney injury are the starting points of preventive therapy and risk stratification.Because of the unreliability of serum creatinine in critically ill patients the development of new biomarkers raises hope. But none of the promising candidates is used in clinical routine up to now. For evaluation of clinical benefit the results of large prospective multicenter studies have to be awaited.© Georg Thieme Verlag Stuttgart · New York.
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