• Alexandre Cochet, Alain Lalande, Paul M Walker, Christophe Boichot, Renaud Ciappuccini, Yves Cottin, Jean-Eric Wolf, and François Brunotte.
• Unité d'IRM et LE2I (CNRS UMR 5158), CHU Hôpital d'enfants, Dijon, France. alexandre.cochet@neuf.fr
• Invest Radiol. 2007 Jun 1; 42 (6): 372-6.

ObjectivesTo evaluate phase-sensitive reconstructed images versus magnitude images generated by an inversion recovery pulse sequence for the determination of myocardial infarct size in delayed-enhancement cardiac magnetic resonance (DE-CMR) at 3 T.Materials And MethodsThirty patients were examined at 3 T and DE images were obtained 10 minutes after contrast agent administration using a phase-sensitive breath-hold segmented inversion recovery gradient echo sequence. From magnitude and phase images, the percentage of hyperenhanced myocardium was expressed. Contrast-to-noise ratio (CNR) measurements were performed in hyperenhanced and normal myocardium.ResultsWe observed excellent correlation and concordance between hyperenhanced myocardium determined on phase-sensitive reconstructed and magnitude images. The mean CNR values were significantly higher in phase-sensitive reconstructed images compared with magnitude images (10.5 +/- 5.4 vs. 6.1 +/- 4.8; P < 0.001).ConclusionsDE-CMR with phase-sensitive reconstruction at 3.0 T provides similar results to magnitude images, but with a significantly greater CNR between infarcted and normal myocardium.

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