• Neurologic clinics · Feb 2021

    Review

    Update in the Management of Myasthenia Gravis and Lambert-Eaton Myasthenic Syndrome.

    • Cynthia Bodkin and Robert M Pascuzzi.
    • Clinical Neurology, Physical Medical Rehabilitation, Indiana University School of Medicine, Indiana University Health, Indianapolis, IN, USA. Electronic address: cbodkin@iu.edu.
    • Neurol Clin. 2021 Feb 1; 39 (1): 133-146.

    AbstractMyasthenia gravis (MG) and Lambert-Eaton myasthenic syndrome (LEMS) are the most common disorders of neuromuscular transmission in clinical practice. Disorders of the neuromuscular junction (NMJ) are characterized by fluctuating and fatigable weakness and include autoimmune, toxic, and genetic conditions. Adults with NMJ disorders are most often antibody mediated, with MG being the most common, having a prevalence of approximately 1 in 10,000, and with women being affected about twice as often as men. This article focuses on advances in management of autoimmune MG and LEMS.Copyright © 2020 Elsevier Inc. All rights reserved.

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