• Anti-cancer drugs · Aug 2000

    Case Reports

    Use of docetaxel (Taxotere) in patients with paclitaxel (Taxol) hypersensitivity.

    • C Moon, C F Verschraegen, M Bevers, R Freedman, A P Kudelka, and J J Kavanagh.
    • Department of Internal Medicine Specialities, University of Texas MD Anderson Cancer Center, Houston 77030, USA.
    • Anticancer Drugs. 2000 Aug 1; 11 (7): 565-8.

    AbstractAnaphylaxis or significant hypersensitivity reaction is one of the most catastrophic potential complications of chemotherapy. There is a 2-5% risk of hypersensitivity with paclitaxel, a commonly used chemotherapeutic agent for various cancers. Three patients, who developed hypersensitivity to paclitaxel infusion, received docetaxel without allergic reactions. Docetaxel may therefore be an alternative treatment for patients with paclitaxel hypersensitivity.

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