• Mov. Disord. · Sep 2003

    Case Reports

    Bilateral subthalamic nucleus deep brain stimulation for advanced PD: correlation of intraoperative MER and postoperative MRI with neuropathological findings.

    • George J Counelis, Tanya Simuni, Mark S Forman, Jurg L Jaggi, John Q Trojanowski, and Gordon H Baltuch.
    • Department of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA.
    • Mov. Disord. 2003 Sep 1; 18 (9): 1062-5.

    AbstractThis postmortem study correlated intraoperative subthalamic nucleus (STN) deep brain stimulation (DBS) placement and postoperative magnetic resonance imaging (MRI) with autopsy findings in a patient who died suddenly 4 days postoperatively from a pulmonary embolism. The study demonstrates that (1) MRI stereotactic localization combined with microelectrode recording (MER) is an accurate way to target STN; (2) multiple MER tracts do not cause significant injury to the brain; and (3) postoperative MRI accurately demonstrates location of the DBS electrodes.Copyright 2003 Movement Disorder Society

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