• Critical care medicine · Aug 1982

    Comparative Study

    Effects of conventional and high frequency jet ventilation on lung parenchyma.

    • M Keszler, R Klein, L McClellan, D Nelson, and M Platt.
    • Crit. Care Med. 1982 Aug 1; 10 (8): 514-6.

    AbstractDespite the increasing acceptance of high frequency jet ventilation (HFJV), very little work has been done to determine if lung damage results from its use. We performed an experimental study to compare the effects of conventional ventilation with those of HFJV on the lung parenchyma of anesthetized dogs. Thirteen animals were studied for periods ranging from 2-24 h. Using a double-lumen Carlen's endotracheal tube, each animals's lungs were ventilated simultaneously but independently, one with conventional ventilation, the other with HFJV. No gross or microscopic evidence of atelectasis or barotrauma was noted in either group. Less hyperaeration was seen in the majority of jet ventilated lungs compared to the conventionally ventilated. In no case did the jet ventilated side show more damage than the control. We concluded that it is possible to use HFJV for 24 h without apparent parenchymal lung damage. Reduced hyperaeration is identified as a possible advantage of HFJV over conventional methods.

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