• Cancer investigation · Jan 2021

    Review Case Reports

    Course of Sars-CoV2 Infection in Patients with Cancer Treated with anti-PD-1: A Case Presentation and Review of the Literature.

    • Laura Pala, Fabio Conforti, Emilia Cocorocchio, Pierfrancesco Ferrucci, Martino Tommaso De Pas, Sara Stucchi, Matteo Repetto, Maristella Saponara, and Paola Queirolo.
    • Division of Medical Oncology for Melanoma, Sarcoma, and Rare Tumors, IEO, European Institute of Oncology IRCCS, Milan, Italy.
    • Cancer Invest. 2021 Jan 1; 39 (1): 9-14.

    AbstractThe outbreak of COVID-19 pandemia is a major health worldwide concern. Patients with cancer might have a worse outcome, because of the immunosuppression determined by the tumor itself and anti-cancer treatments, including chemotherapy and radiotherapy. The impact and course of viral infection in patients receiving immunotherapy remains unknown. We report the case of a patient with metastatic melanoma, long responder to anti PD-1 blockade who got infected with Sars CoV-2, recovering without sequelae. A critical review of literature was performed. Limited data available in literature support the possibility to continue the immunotherapy in patients with cancer under control.

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