• Clinics · Jan 2021

    Review

    Extrapulmonary onset manifestations of COVID-19.

    • Josef Finsterer, Fulvio A Scorza, Carla A Scorza, and FioriniAna CAC0000-0003-2989-2308Programa de Estudos Pos-Graduados em Fonoaudiologia, Pontificia Universidade Catolica de Sao Paulo (PUC-SP), Sao Paulo, SP, BR, Departamento de Fonoaudiologia, Escola Paulista de Medicina/Universidade Federal de Sao Paulo .
    • Klinik Landstrasse, Messerli Institute, Vienna, Austria.
    • Clinics (Sao Paulo). 2021 Jan 1; 76: e2900e2900.

    AbstractCoronavirus disease (COVID-19) usually starts with pulmonary signs and symptoms. However, in some cases, the initial clinical presentations are extrapulmonary. This literature review aimed at summarizing and discussing the extrapulmonary onset manifestations of COVID-19. The most frequent initial extrapulmonary manifestations include hypogeusia, hyposmia, non-specific abdominal symptoms, corneal congestion, and deep venous thrombosis. Several rarer extrapulmonary manifestations in locations such as the brain, peripheral nerves, muscles, eyes, ears, myocardium, intestines, skin, or vessels have been additionally reported as onset presentations of COVID-19. In conclusion, it is crucial for clinicians and health care providers to consider extrapulmonary presentations at the onset of COVID-19 to avoid overlooking the infection and contributing to the spread of the disease.

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