• Hawaii medical journal · Mar 2007

    Case Reports

    Eosinophilic fasciitis in a 57-year-old Japanese-American woman.

    • Deryll U Ambrocio and Kristine Uramoto.
    • Department of Internal Medicine, University of Hawai'i John A. Burns School of Medicine, Honolulu, HI 96813, USA. dambrocio@gmail.com
    • Hawaii Med J. 2007 Mar 1; 66 (3): 64-6.

    AbstractEosinophilic fasciitis (EF) is a rare connective tissue disorder characterized by symmetrical sclerodermatous skin changes primarily affecting the extremities and histologically, by thickening of the fascia with chronic inflammatory infiltrate containing eosinophils. EF is associated with peripheral eosinophilia, hypergammaglobulinemia, and an elevated ESR. Reported is a case of EF in a 57-year-old Japanese-American woman who refused treatment with prednisone, review of other treatment options, and discussion of key differences between this disease and scleroderma.

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