-
Review Meta Analysis
Meta-analysis of intravenous lidocaine and postoperative recovery after abdominal surgery.
- E Marret, M Rolin, M Beaussier, and F Bonnet.
- Department of Anaesthesiology and Intensive Care, Tenon University Hospital, Assistance Publique-Hôpitaux de Paris, Unité Institut National de la Santé et de la Recherche Médicale U707, Paris, France. emmanuel.marret@tnn.ap-hop-paris.fr
- Br J Surg. 2008 Nov 1;95(11):1331-8.
BackgroundContinuous intravenous administration of lidocaine may decrease the duration of ileus and pain after abdominal surgery.MethodsThree databases (Medline, Embase and the Cochrane Controlled Trials Register) were searched to retrieve randomized controlled trials comparing continuous intravenous lidocaine infusion during and after abdominal surgery with placebo. Study design was scored using the Oxford Quality Score based on randomization, double-blinding and follow-up. Outcome measures were duration of ileus, length of hospital stay, postoperative pain, and incidence of nausea and vomiting.ResultsEight trials were selected. A total of 161 patients received intravenous lidocaine, with 159 controls. Intravenous lidocaine administration decreased the duration of ileus (weighted mean difference (WMD) - 8.36 h; P < 0.001), length of hospital stay (WMD - 0.84 days; P = 0.002), postoperative pain intensity at 24 h after operation on a 0-100-mm visual analogue scale (WMD - 5.93 mm; P = 0.002), and the incidence of nausea and vomiting (odds ratio 0.39; P = 0.006).ConclusionContinuous intravenous administration of lidocaine during and after abdominal surgery improves patient rehabilitation and shortens hospital stay.Copyright (c) 2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
Notes
Knowledge, pearl, summary or comment to share?You can also include formatting, links, images and footnotes in your notes
- Simple formatting can be added to notes, such as
*italics*
,_underline_
or**bold**
. - Superscript can be denoted by
<sup>text</sup>
and subscript<sub>text</sub>
. - Numbered or bulleted lists can be created using either numbered lines
1. 2. 3.
, hyphens-
or asterisks*
. - Links can be included with:
[my link to pubmed](http://pubmed.com)
- Images can be included with:

- For footnotes use
[^1](This is a footnote.)
inline. - Or use an inline reference
[^1]
to refer to a longer footnote elseweher in the document[^1]: This is a long footnote.
.