• Expert Rev Anticancer Ther · Nov 2006

    Review

    Recurrent glioblastoma multiforme: advances in treatment and promising drug candidates.

    • Lijo Simpson and Evanthia Galanis.
    • Mayo Clinic, Department of Oncology, 200 1st Str SW, Rochester, MN 55905, USA. simpson.lijo@mayo.edu
    • Expert Rev Anticancer Ther. 2006 Nov 1; 6 (11): 1593-607.

    AbstractRecurrent glioblastoma multiforme is a lethal disease with currently available treatment options having a limited impact on outcome. In this article, current and novel therapeutic approaches in the treatment of recurrent glioblastoma multiforme, including chemotherapy, targeted molecular agents, virotherapy/gene therapy and immunotherapy and challenges in developing novel therapeutic agents for glioblastoma multiforme will be discussed.

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