• Young Jin Kim, Dong Hee Koh, Se Woo Park, Sun Man Park, Min Ho Choi, Hyun Joo Jang, Sea Hyub Kae, Jin Lee, and Hyun Woo Byun.
• Hepato Gastroenterol. 2014 Nov 1; 61 (136): 2256-9.

Background/AimsTo determine the risk factors, causes, and outcome of clinically important upper gastrointestinal bleeding that occurs in severely burned patients.MethodologyThe charts of all patients admitted to the burn intensive care unit were analyzed retrospectively over a 4-year period (from January 2006 to December 2009). Cases consisted of burned patients who developed upper gastrointestinal bleeding more than 24 hours after admission to the burn intensive care unit. Controls were a set of patients, in the burn intensive care unit, without upper gastrointestinal bleeding matched with cases for age and gender. Cases and controls were compared with respect to the risk factors of upper gastrointestinal bleeding and outcomes.ResultsDuring the study period, clinically important upper gastrointestinal bleeding occurred in 20 patients out of all 964 patients. The most common cause of upper gastrointestinal bleeding was duodenal ulcer (11 of 20 cases, 55%). In the multivariate analysis, mechanical ventilation (p = 0.044) and coagulopathy (p = 0.035) were found to be the independent predictors of upper gastrointestinal bleeding in severely burned patients.ConclusionsUpper gastrointestinal hemorrhage tends to occur more frequently after having prolonged mechanical ventilation and coagulopathy.

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