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J Dtsch Dermatol Ges · Apr 2009
Case ReportsTelangiectasia macularis eruptiva perstans, a form of cutaneous mastocytosis, associated with malignant melanoma.
- Lutz Kowalzic, Lena Eickenscheidt, Christoph Seidel, Sabine Kribus, Heidrun Ziegler, and Michael Komar.
- Department of Dermatology and Allergy, HELIOS Vogtland Clinic Plauen Ltd., Plauen, Germany. lutz.kowalzick@helioskliniken.de
- J Dtsch Dermatol Ges. 2009 Apr 1;7(4):360-2.
AbstractA 62-year-old obese woman presented with a malignant melanoma (Stage la). In addition, she had disseminated telangiectatic macules on both thighs. Intensive rubbing of lesions resulted in wheals. Biopsy revealed increased numbers of mast cells. We diagnosed telangiectasia macularis eruptiva perstans, a rare clinical form of adult maculopapular cutaneous mastocytosis, a group which also includes urticaria pigmentosa. No evidence was found for systemic involvement. Possible associations with malignant tumors and the possible role of c-kit mutations both in development of melanoma and mastocytosis are discussed.
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