• Anti-cancer drugs · Aug 2000

    Case Reports

    Paclitaxel-induced remission in docetaxel-refractory anthracycline-pretreated metastatic breast cancer.

    • T Suzuma, T Sakurai, G Yoshimura, T Umemura, T Tamaki, and Y Naito.
    • Department of Surgery, Affiliated Kihoku Hospital, Wakayama Medical College, Itogun, Japan. suzuma@mail.wakayama-med.ac.jp
    • Anticancer Drugs. 2000 Aug 1; 11 (7): 569-71.

    AbstractPaclitaxel and docetaxel are excellent agents with a high antitumor effect for the treatment of previously anthracycline-exposed metastatic breast cancer. There has been no standard treatment for patients who undergo therapy of a taxan-resistant metastatic breast cancer. Paclitaxel has partial non-cross-resistance in vitro with docetaxel in inhibiting microtubule disaggregation. We present the case of a patient with docetaxel-refractory anthracycline-pretreated metastatic breast cancer who achieved remission with paclitaxel.

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