• J Dtsch Dermatol Ges · Jul 2007

    Practice Guideline

    Evidence-based (S3) guidelines for the treatment of psoriasis vulgaris.

    • Alexander Nast, Ina B Kopp, Matthias Augustin, Kirstin-Benita Banditt, Wolf-Henning Boehncke, Markus Follmann, Markus Friedrich, Matthias Huber, Christina Kahl, Joachim Klaus, Joachim Koza, Inga Kreiselmaier, Johannes Mohr, Ulrich Mrowietz, Hans-Michael Ockenfels, Hans-Dieter Orzechowski, Jörg Prinz, Kristian Reich, Thomas Rosenbach, Stefanie Rosumeck, Martin Schlaeger, Gerhard Schmid-Ott, Michael Sebastian, Volker Streit, Tobias Weberschock, Berthold Rzany, Deutsche Dermatologische Gesellschaft (DDG), and Berufsverband Deutscher Dermatologen (BVDD).
    • Division of Evidence Based Medicine (dEBM), Klinik für Dermatologie, Venerologie und Allergologie, Charité-Universitätsmedizin Berlin, Germany.
    • J Dtsch Dermatol Ges. 2007 Jul 1; 5 Suppl 3: 1-119.

    AbstractPsoriasis vulgaris is a common and often chronic inflammatory skin disease. The incidence of psoriasis in Western industrialized countries ranges from 1 to 2%. Patients afflicted with severe psoriasis vulgaris may experience a significant reduction in quality of life. Despite the large variety of treatment options available, patient surveys have revealed lack of satisfaction with the efficacy of available treatments and a high rate of non-compliance. To optimize the treatment of psoriasis in Germany, the Deutsche Dermatologische Gesellschaft (DDG) and the Berufsverband Deutscher Dermatologen (BVDD) initiated a project to develop evidence-based guidelines for the management of psoriasis. These resulting Guidelines focus on induction therapy in cases of mild, moderate, and severe plaquetype psoriasis in adults. The Guidelines include evidence-based evaluation of the efficacy of all currently available therapeutic options in Germany. In addition, they offer detailed information on how best to administer the various treatments and give information on contraindications, adverse drug reactions, and drug interactions as well as estimates of practicability and cost. The Guidelines were developed following the recommendations of the Arbeitsgemeinschaft wissenschaftlicher medizinischer Fachgesellschaften (AWMF). The therapeutic recommendations were developed by an expert group and finalized during interdisciplinary consensus conferences.

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