• Int J Gynaecol Obstet · Oct 1991

    The use of 16,16-dimethyl-trans-delta 2 prostaglandin E1 methyl ester vaginal suppositories for management of missed abortion and fetal death.

    • F Fruzzetti, G B Melis, L De Cecco, A R Genazzani, and P Fioretti.
    • Department of Obstetrics and Gynecology, Pisa University, Italy.
    • Int J Gynaecol Obstet. 1991 Oct 1; 36 (2): 115-9.

    AbstractThe effect of vaginal administration of a PgE1 analogue to terminate missed abortion and fetal death in utero was evaluated in 62 women with gestation ranging from the 13th to the 37th week. Abortion occurred in 85.4% of women with missed abortion and in 86% of women with fetal death. In both groups, the mean induction time was less than 12 h. The incidence of side effects, primarily gastrointestinal symptoms, was infrequent.

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