• Seminars in perinatology · Mar 2019

    Review

    Uterine factor in recurrent pregnancy loss.

    • Jenna M Turocy and Beth W Rackow.
    • Department of Obstetrics & Gynecology, Columbia University Medical Center, Fertility Center, 5 Columbus Circle, PH, New York, New York, USA. Electronic address: jt3072@cumc.colubia.edu.
    • Semin. Perinatol. 2019 Mar 1; 43 (2): 74-79.

    ObjectiveTo review the current understanding of the role the uterus plays in recurrent pregnancy loss.FindingsCongenital and acquired uterine abnormalities are associated with recurrent pregnancy loss in the first and second trimester. Relevant congenital Mullerian tract anomalies include unicornuate, didelphys, bicornuate and septate uteri. Pregnancy loss has also been associated with acquired uterine abnormalities that distort the uterine cavity such as intrauterine adhesions and submucosal myomas. Initial evaluation of women with recurrent pregnancy loss should include a uterine assessment such as a pelvic ultrasound or sonohysterography. Uterine abnormalities such as uterine septum, intrauterine adhesions and submucosal myomas may be managed surgically with operative hysteroscopy.ConclusionUterine abnormalities, both congenital and acquired, can be responsible for recurrent pregnancy loss.Copyright © 2018. Published by Elsevier Inc.

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