• Curr Treat Options Oncol · Oct 2018

    Review

    Big Data in Head and Neck Cancer.

    • Carlo Resteghini, Annalisa Trama, Elio Borgonovi, Hykel Hosni, Giovanni Corrao, Ester Orlandi, Giuseppina Calareso, Loris De Cecco, Cesare Piazza, Luca Mainardi, and Lisa Licitra.
    • Head and Neck Medical Oncology Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy. carlo.resteghini@istitutotumori.mi.it.
    • Curr Treat Options Oncol. 2018 Oct 25; 19 (12): 62.

    Opinion StatementHead and neck cancers can be used as a paradigm for exploring "big data" applications in oncology. Computational strategies derived from big data science hold the promise of shedding new light on the molecular mechanisms driving head and neck cancer pathogenesis, identifying new prognostic and predictive factors, and discovering potential therapeutics against this highly complex disease. Big data strategies integrate robust data input, from radiomics, genomics, and clinical-epidemiological data to deeply describe head and neck cancer characteristics. Thus, big data may advance research generating new knowledge and improve head and neck cancer prognosis supporting clinical decision-making and development of treatment recommendations.

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