• Seong Yun Kim, Jeong Hyun Lee, Yong Jae Lee, Byung Se Choi, Jin Woo Choi, Hyun Sin In, Sun Mi Kim, and Jung Hwan Baek.
• Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Centre, 388-1 Pungnap2-dong, Songpa-gu, Seoul, 138-736, Korea.
• Eur Radiol. 2010 May 1; 20 (5): 1079-84.

ObjectivesTo determine the diagnostic value of the anterior chamber depth (ACD) of a globe as seen on CT for detecting open-globe injury.MethodsWe enrolled 28 patients with unilateral open-globe injury confirmed by surgery and 28 controls with other types of orbital trauma. The diagnostic value of the difference of the ACDs between globes was evaluated by ROC analysis. The diagnostic performance of the following CT findings suggesting open-globe injury was also determined from independent analysis by two readers, i.e. change in the ACD and the globe contour, obvious volume loss of the globe, dislocated/deformed lens, intraocular foreign body/air and intraocular haemorrhage.ResultsThe ACD measurements were possible only in 15 patients with open-globe injuries. A difference in the ACDs > or =0.4 mm resulted in 0.85 of the area under the ROC curve with a sensitivity of 73% and specificity of 100% (p = 0.0001). The presence of one or more of the CT findings had a sensitivity of 92%, specificity of 85% and diagnostic accuracy of 89%.ConclusionsChange in the ACD is a helpful CT finding for detecting open-globe injury. A difference in the ACDs > or =0.4 mm is a helpful diagnostic criterion with excellent specificity.

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