• Juliane Agustini Orati, Patricia Almeida, Vanessa Santos, Gustavo Ciorla, and Suzana Margareth Lobo.
• Faculdade de Medicina, Universidade de Ribeirão Preto - Ribeirão Preto, Brazil.
• Rev Bras Ter Intensiva. 2013 Mar 1;25(1):6-11.

ObjectivesTo evaluate the C-reactive protein serum levels in patients with pulmonary and abdominal sepsis during the first five days of sepsis progression.MethodsThe present investigation was a retrospective cohort study conducted at the university hospital with 345 patients who were admitted to the intensive care unit and diagnosed with sepsis of pulmonary or abdominal origin. Serum C-reactive protein concentrations were measured by the turbidimetric immunoassay. For analysis of C-reactive protein, day 1 was defined as the day on which the patient was clinically diagnosed with sepsis.ResultsThirty-four patients with sepsis (9.8%), 114 patients with severe sepsis (33.0%), and 197 patients with septic shock (57.2%) were evaluated. The age of the patients was 56.4 ± 19.8 years. The serum C-reactive protein concentrations were higher on the day of sepsis diagnosis in the group with abdominal infection compared with the group with pulmonary sepsis (17.8 ± 10.1 mg/dL versus 14.9 ± 11.1 mg/dL, p=0.025) and remained significantly higher during the first five days of sepsis progression.ConclusionThe serum C-reactive protein concentrations were significantly higher in the patients with abdominal sepsis compared with the patients with pulmonary sepsis during the first five days of sepsis progression.

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