• Rodney K Edwards, Christine A Reed, Kathryn S Villano, Jennifer L Holmes, Suhong Tong, and Jill K Davies.
• Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynecology, University of Alabama, Birmingham School of Medicine, Birmingham, Alabama.
• Am J Perinatol. 2014 Jun 1; 31 (6): 455-62.

ObjectiveTo evaluate the effect of mode and amount of fluid hydration during labor.Study DesignThe authors conducted a randomized controlled trial of uncomplicated nulliparous women in spontaneous labor at 36 weeks or more gestational age. Women were randomized to receive lactated Ringer solution with 5% dextrose at (1) 125 mL/h intravenously with limited oral intake, (2) 250 mL/h intravenously with limited oral intake, or (3) 25 mL/h intravenously with ad libitum oral intake of clear liquids. Results were analyzed by intent-to-treat analysis.ResultsA total of 311 out of 324 women were available for analysis. Groups 1 (n = 105), 2 (n = 105), and 3 (n = 101) above did not differ significantly for mean labor duration (11.6 ± 5.9, 11.4 ± 5.5, and 11.5 ± 5.9 hours, respectively; p = 0.998), proportion of women in labor > 12 hours (all groups 41%; p = 0.998), proportion receiving oxytocin augmentation (59, 60, and 57%, respectively; p = 0.923), or proportion delivered by cesarean (22, 17, and 17%, respectively; p = 0.309). Indications for cesarean were similar between groups. No cases of pulmonary edema, maternal aspiration, or perinatal mortality occurred.ConclusionAlthough apparently safe, neither increased intravenous hydration nor oral hydration during labor improves labor performance.Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

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