• Arch Mal Coeur Vaiss · Dec 2000

    [Anomalties of the interatrial septum and latent atrial vulnerability in unexplained ischemic stroke in young adults].

    • E Somody, J F Albucher, G Casteignau, N Prouteau, A Danielli, M Delay, F Chollet, and J Puel.
    • Service de cardiologie B, CHU Purpan, place du Docteur-Baylac, 31059 Toulouse.
    • Arch Mal Coeur Vaiss. 2000 Dec 1; 93 (12): 1495-500.

    AbstractSeventy-four consecutive patients (18 to 55 years) underwent programmed atrial stimulation in the investigation of unexplained ischaemic stroke after a full work-up including transoesophageal echocardiography to exclude abnormalities of the interatrial septum (patent foramen ovale and/or atrial septal aneurysm). The parameters recorded during atrial electrophysiological investigation were: the effective atrial refractory period, loco-regional intra-atrial conduction, the index of latent atrial vulnerability and the inducibility by the extrastimulus technique. Seventy five per cent of patients with a patent foramen ovale and/or an atrial septal aneurysm were inducible compared with only 38% of patients with normal interatrial septa on transoesophageal echocardiography (p = 0.001). Fifty two per cent of patients with an anomaly of the atrial septum had latent atrial vulnerability compared with 26% of those with normal transoesophageal echocardiography (p = 0.02). These results confirm the relationship between atrial septal anomalies and latent atrial vulnerability in unexplained ischaemic stroke of young adults.

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