• Clinical cardiology · Nov 2020

    Review

    COVID-19 and the heart: An update for clinicians.

    • Ahmed Goha, Kenechukwu Mezue, Paul Edwards, Felix Nunura, Dainia Baugh, and Ernest Madu.
    • Aga Khan University Hospital, Nairobi, Kenya.
    • Clin Cardiol. 2020 Nov 1; 43 (11): 1216-1222.

    AbstractSARS-CoV-2, the cause of the COVID-19 pandemic has significantly impacted cardiovascular healthcare. Patients with pre-existing cardiovascular disease are at higher risk of morbidity and mortality. The virus may affect the heart directly and indirectly with clinical syndromes of acute myocardial injury, myocarditis, acute coronary syndromes, heart failure, arrhythmias, and venous thromboembolism. Some therapeutics under investigation for COVID-19 may also have adverse cardiac effects. The involvement of the RAAS system in viral entry makes it pertinent to consider the effects of medications that modulate the system. Comprehensive knowledge of peculiar cardiovascular manifestations of COVID-19 and the role of RAAS in the prognosis of COVID-19 disease is needed for optimal patient management.© 2020 The Authors. Clinical Cardiology published by Wiley Periodicals, Inc.

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