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Int J Gynaecol Obstet · Jan 2020
Multicenter StudyPatient characteristics and pregnancy outcomes among Zika-infected pregnant women: Epidemiologic surveillance data from two cities in Colombia, 2015-2016.
- Jovana A Ocampo Cañas, David Caviedes Combita, Helvert F Molina Leon, Andrés M Garcia Sierra, and Luis J Hernández Florez.
- Public Health, Medical Education, and Professionalism Research group, School of Medicine, University of Los Andes, Bogotá, Colombia.
- Int J Gynaecol Obstet. 2020 Jan 1; 148 Suppl 2: 4-8.
ObjectivesTo describe the characteristics of pregnant women infected with Zika virus in two representative regions of Colombia, examine their pregnancy outcomes, and outline findings of the epidemiologic surveillance program established during the peak of the 2015-2016 epidemic.MethodsA cohort study conducted in the municipalities of Cali and Villavicencio using data from the National Public Health Surveillance System (SIVIGILA) and clinical follow-up data from pregnant women. We describe sociodemographic characteristics, health insurance status, Zika virus, pregnancy-related characteristics, and pregnancy outcomes.ResultsA total of 1259 Zika-infected pregnant women were identified in Cali; of these, 2.3% (n=27) experienced pregnancy loss, 9.5% (n=113) had preterm birth, and 7.9% (n=91) had a low birthweight neonate. In Villavicencio, 3.0% (n=13) experienced pregnancy loss, 6.9% (n=30) had preterm birth, and 6.7% (n=28) had a low birthweight neonate. Compared with the general population, this population of Zika-infected pregnant women did not experience an increased frequency of preterm birth or low birthweight (relative risk of prematurity and low birthweight infant <1).ConclusionsEpidemiologic surveillance data showed that most neonates of Zika-infected pregnant women were born at term, and that the frequency of low birthweight neonates was low. Good quality data were obtained from the surveillance registries.© 2020 World Health Organization; licensed by John Wiley & Sons Ltd on behalf of International Federation of Gynecology and Obstetrics.
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