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- A Grau-Perales, B Gómez-Chacón, E Morillas, and M Gallo.
- Departamento de Psicobiología, Instituto de Neurociencias, Centro de Investigación Biomédica, Universidad de Granada, Spain. Electronic address: abgrau@ugr.es.
- Behav. Brain Res. 2019 Mar 15; 360: 196-201.
AbstractThe relationship between the piriform cortex and flavor recognition memory was investigated in adult and aged rats. By using c-Fos immunohistochemistry, we assessed the piriform cortex activity induced by flavor familiarity. The results indicated increased activity in the rostral region of the posterior piriform cortex elicited by the most familiar cider vinegar solution after six exposures. Aged rats exhibited overall increased activity in the posterior, but not the anterior piriform cortex, which was not related to flavor familiarity. This suggests that the posterior piriform cortex is related to flavor recognition memory and that aging modifies its activity pattern which might underlie their slower attenuation of flavor neophobia.Copyright © 2018 The Authors. Published by Elsevier B.V. All rights reserved.
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