• Masui · Oct 2009

    Case Reports

    [Perioperative management of a patient with Parkinson's disease with intravenous infusion of levodopa].

    • Ju Mizuno, Shinya Kato, Minako Watada, and Shigeho Morita.
    • Department of Anesthesiology, Teikyo University School of Medicine, Tokyo 173-8605.
    • Masui. 2009 Oct 1;58(10):1286-9.

    AbstractParkinson's disease is a disorder of the extrapyramidal system resulting from the deficiency of dopamine in the basal ganglia. We experienced the perioperative management of a patient with Parkinson's disease with intravenous infusion of levodopa, precursor of which is dopamine. A 73-year-old woman with Parkinson's tremor in her bilateral fingers of Hoehn and Yahr stage II was scheduled for repair of bladder prolapse under general anesthesia. Antiparkinson drug levodopa/dopa decarboxylase inhibitor (carbidopa) 400 mg per day had been administered orally to control her bilateral tremor. Three hours before the operation, oral medication including levodopa/carbidopa 100 mg was withdrawn, and intravenous infusion of levodopa 100mg was started. Without any premedication, anesthesia was induced with intravenous infusion of propofol, fentanyl, and vecuronium, and tracheal intubation was facilitated. Anesthesia was maintained with inhalation of air, oxygen, and sevoflurane, and intravenous infusion of fentanyl. After emergence, we found no neurological disorders excluding her tremor. Levodopa/carbidopa 100 mg was readministered orally four hours after the operation and total of 300 mg had been administered orally on the operative day. Levodopa/carbidopa 400 mg per day had been administered orally after the first operative day. She did not show deterioration of her symptom of Parkinson's disease, and develop any complications during the perioperative period. We need to manage Parkinson's disease with intravenous infusion of levodopa during the perioperative period, taking care of the symptom of Parkinson's disease and the occurrence of complications.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.

We guarantee your privacy. Your email address will not be shared.