• José V Manjón, Pierrick Coupé, Luis Martí-Bonmatí, D Louis Collins, and Montserrat Robles.
• Instituto de Aplicaciones de las Tecnologías de la Información y de las Comunicaciones Avanzadas (ITACA), Universidad Politécnica de Valencia, Valencia, Spain. jmanjon@fis.upv.es
• J Magn Reson Imaging. 2010 Jan 1; 31 (1): 192-203.

PurposeTo adapt the so-called nonlocal means filter to deal with magnetic resonance (MR) images with spatially varying noise levels (for both Gaussian and Rician distributed noise).Materials And MethodsMost filtering techniques assume an equal noise distribution across the image. When this assumption is not met, the resulting filtering becomes suboptimal. This is the case of MR images with spatially varying noise levels, such as those obtained by parallel imaging (sensitivity-encoded), intensity inhomogeneity-corrected images, or surface coil-based acquisitions. We propose a new method where information regarding the local image noise level is used to adjust the amount of denoising strength of the filter. Such information is automatically obtained from the images using a new local noise estimation method.ResultsThe proposed method was validated and compared with the standard nonlocal means filter on simulated and real MRI data showing an improved performance in all cases.ConclusionThe new noise-adaptive method was demonstrated to outperform the standard filter when spatially varying noise is present in the images.(c) 2009 Wiley-Liss, Inc.

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