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Curr Probl Diagn Radiol · Sep 2018
ReviewReview of Extraskeletal Activity on Tc-99m Methylene Diphosphonate Bone Scintigraphy and Value of Cross-Sectional and SPECT-CT Imaging Correlation.
- Mohammed Bermo, Sanaz Behnia, Joanna Fair, Robert S Miyaoka, and Saeed Elojeimy.
- Department of Radiology, University of Washington Medical Center, Seattle, WA.
- Curr Probl Diagn Radiol. 2018 Sep 1; 47 (5): 324-332.
AbstractRecognizing the different mechanisms and imaging appearance of extraskeletal Tc-99m methylene diphosphonate uptake enhances the diagnostic value of bone scan interpretation. In this article, we present a pictorial review of the different mechanisms of extraskeletal Tc-99m methylene diphosphonate uptake on bone scintigraphy including neoplastic, inflammatory, ischemic, traumatic, excretory, and iatrogenic. We also illustrate through case examples the added value of correlation with cross-sectional and single photon emission computed tomography and computed tomography imaging in localizing and characterizing challenging cases of extraskeletal uptake.Copyright © 2018 Elsevier Inc. All rights reserved.
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